Labs that have to deposit complete protocols, starting with open-science funders.
Funders have turned protocol completeness into a condition of the money. ASAP, the Aligning Science Across Parkinson's initiative, requires protocols behind funded publications to be deposited on a sharing service under CC BY. NIH's Data Management and Sharing Policy points every NIH grantee the same way. The first cohort is Parkinson's labs funded under those policies; the second is any NIH-funded lab with a by-eye analysis step.
The alternative is a hire
Turning what a scientist knows into something a computer can run has meant hiring a computational person, paying a core facility by the hour, or losing a grant cycle to a failed reproduction. A lab can budget Methods as a line item inside a modular grant and keep the scientist as the knowledge authority.
The scientist stays the authority
A scientist with a discovery can build computational support into the budget far more cheaply than a hire, and does not hand the analysis to someone who does not know the science. Methods drafts; the scientist validates.
Where the incumbents stop
Notebooks and protocol repositories are storage: they wait to be filled in, and their newer AI features structure what a scientist already wrote. Nothing we have found interviews the scientist about what was never written down.
Same engine, second product
The guided-elicitation engine behind Methods was built to work anywhere expertise lives in one person's head. The second product on it, for owner-operated service businesses, is on the roadmap after the scientific cohort.